Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 4/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133840 | 0.96 | SYK (0.53) | SYKITKCHEK2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4129766 | 0.93 | SYK (0.46) | SYKITKCHEK2KDM4EALDH1A1 | |
| SCHEMBL4142555 | 0.91 | SYK (0.49) | SYKITKCHEK2FGFR1FLT1 | |
| Hydrochloric Acid SCHEMBL4134722 | 0.90 | SYK (0.49) | SYKITKCHEK2FGFR1FLT1 | |
| Trifluoroacetic Acid SCHEMBL4122410 | 0.89 | CHEK2 (0.36) | SYKITKCHEK2MEN1KMT2A | |
| SCHEMBL4133817 | 0.88 | SYK (0.50) | SYKITKCHEK2FGFR1FLT1 | |
| SCHEMBL3924905 | 0.84 | CHEK2 (0.39) | SYKITKCHEK2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4134146 | 0.83 | SYK (0.49) | SYKITKCHEK2KDM4EHRH4 | |
| Trifluoroacetic Acid SCHEMBL4130010 | 0.80 | SYK (0.43) | SYKITKMEN1KMT2AFGFR1 | |
| SCHEMBL3934547 | 0.79 | ITK (0.46) | SYKITKCHEK2FGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126969-B2 | Pyrazolylbenzimidazole derivatives, compositions containing them and use thereof | AVENTIS PHARMA S.A. (FR) | 2015-09-08 | — | — | US | disclosed |
| US-20090197866-A1 | PYRAZOLYLBENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197866-A1 | PYRAZOLYLBENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND USE THEREOF | RB1, CCNI, CDK2 | SYK 392/4885ITK 1817/4885CHEK2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.