SCHEMBL4137353

SCHEMBL4137353

C=C(CO)CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11439577 0.96
SCHEMBL1070929 0.84
Ammonia Solution, Strong SCHEMBL2637991 0.80 TSHR (0.31)
SCHEMBL9086148 0.79
SCHEMBL229980 0.74
SCHEMBL17882161 0.72
SCHEMBL909946 0.72
SCHEMBL8923802 0.72
SCHEMBL17882163 0.72
SCHEMBL887897 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004093891-A1 VEGETABLE EXTRACT COMPOSITIONS COMPRISING INODOLE ACETIC, METHODS FOR THE PREPARATION OF SAID COMPSITIONS, AND THEIR USE AS CELL GROWTH INHIBITING AGENTS VEIJLEN N.V. (AN) 2004-11-04 WO claimed
EP-0153720-B1 SPERGUALIN-RELATED COMPOUNDS HAVING A PHENYLENE GROUP, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1988-11-09 EP claimed
EP-0153720-A2 Spergualin-related compounds having a phenylene group, a process for their preparation and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1985-09-04 EP claimed
CN-115322124-B Synthesis method of 2-methylene butane-1, 4-dimethyl disulfonate 凯美克(上海)医药科技有限公司 2023-12-22 CN disclosed
US-20220409589-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY GENZYME CORP (US) 2022-12-29 US disclosed
CN-108976106-B (E) Synthesis method of (E) -2-methylene-1, 4-butanedione compounds 河南师范大学 2021-02-19 CN disclosed
US-10633591-B2 Flame retardant itaconic acid-based compounds INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-04-28 US disclosed
US-10322111-B2 Chemokine receptor binding heterocyclic compounds with enhanced efficacy GENZYME CORPORATION (US) 2019-06-18 US disclosed
US-20190106633-A1 FLAME RETARDANT ITACONIC ACID-BASED COMPOUNDS INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-04-11 US disclosed
EP-1465889-B1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY GENZYME CORP (US) 2017-03-22 EP disclosed
US-20160228413-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY ANORMED INC. (CA) 2016-08-11 US disclosed
EP-0503896-B1 Spiroorthocarbonate compound and polymers obtained therefrom KURARAY CO (JP) 1999-01-07 EP disclosed
WO-1994027992-A1 PIPERIDINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1994-12-08 WO disclosed
US-5298631-A Polymers for molding materials KURARAY CO., LTD. (JP) 1994-03-29 US disclosed
EP-0503896-A1 Spiroorthocarbonate compound and polymers obtained therefrom KURARAY CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0153720-B1 SPERGUALIN-RELATED COMPOUNDS HAVING A PHENYLENE GROUP, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1988-11-09 EP disclosed
US-4556735-A BACTERICIDE, ANTITUMOR AGENT ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1985-12-03 US disclosed
EP-0153720-A2 Spergualin-related compounds having a phenylene group, a process for their preparation and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1985-09-04 EP disclosed
EP-0036160-B1 PROCESS FOR THE PREPARATION OF 2-HYDROXYALKYL CHROMANES BASF Aktiengesellschaft (DE) 1983-05-11 EP disclosed
US-4344886-A ETHERIFICATION, ALKYLATION, LEWIS ACID CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed