Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440604 | 0.83 | NR4A2 (0.66) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17782448 | 0.83 | NR4A2 (0.70) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL2000654 | 0.81 | NR4A2 (0.63) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6298233 | 0.80 | NR4A2 (0.61) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL408819 | 0.80 | NR4A2 (1.00) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3405495 | 0.79 | NR4A2 (0.56) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13209353 | 0.77 | NR4A2 (0.65) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4239994 | 0.76 | NR4A2 (0.60) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4243232 | 0.76 | NR4A2 (0.56) | NR4A2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3681206 | 0.76 | NR4A2 (0.68) | NR4A2KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071577-A1 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |