Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11536415 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5292001 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL961145 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5289993 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5291547 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5286003 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5288554 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5301568 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5298507 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 | |
| SCHEMBL5290111 | 0.98 | MEN1 (0.54) | SMN1; SMN2MEN1HSP90AA1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758639-B2 | Electrolyte composition with a low gelling temperature and method for manufacturing electronic device using the same | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2014-06-24 | — | — | US | disclosed |
| US-20120018077-A1 | Electrolyte composition with a low gelling temperature and method for manufacturing electronic device using the same | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2012-01-26 | — | — | US | disclosed |