⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321148 | 0.77 | — | — | |
| SCHEMBL15137935 | 0.75 | — | — | |
| SCHEMBL712506 | 0.75 | EPHX1 (0.33) | — | |
| SCHEMBL909268 | 0.75 | — | — | |
| SCHEMBL11575260 | 0.75 | — | — | |
| SCHEMBL14553992 | 0.73 | — | — | |
| SCHEMBL14321457 | 0.71 | — | — | |
| SCHEMBL14552433 | 0.71 | — | — | |
| SCHEMBL6737496 | 0.71 | — | — | |
| SCHEMBL21582231 | 0.69 | EPHX1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12176572-B2 | In situ formation of solid-state polymer electrolytes for batteries | CORNELL UNIVERSITY (US) | 2024-12-24 | — | — | US | disclosed |
| US-20220085455-A1 | IN SITU FORMATION OF SOLID-STATE POLYMER ELECTROLYTES FOR BATTERIES | CORNELL UNIVERSITY | 2022-03-17 | — | — | US | disclosed |
| US-20170114075-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-04-27 | — | — | US | disclosed |
| US-9458178-B2 | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2016-10-04 | — | — | US | disclosed |
| US-20160002244-A1 | OXIDATED DERIVATIVES OF TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2A RECEPTOR AND THEIR USE AS MEDICAMENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2016-01-07 | — | — | US | disclosed |
| EP-2942350-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2015-11-11 | — | — | EP | disclosed |
| US-20150291623-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2015-10-15 | — | — | US | disclosed |
| US-9133197-B2 | Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2015-09-15 | — | — | US | disclosed |
| EP-2408775-B1 | OXIDATED DERIVATIVES OF TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2A RECEPTOR AND THEIR USE AS MEDICAMENTS | SIGMA TAU IND FARMACEUTI (IT) | 2015-06-17 | — | — | EP | disclosed |
| EP-2350090-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2015-06-03 | — | — | EP | disclosed |
| EP-0283309-B1 | 1,2-1,4 Addition reaction sequence leading to diphenylacetylenes | MCNEILAB INC (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0375457-B1 | Cyclic ether derivatives | ICI PLC (GB) | 1994-03-16 | — | — | EP | disclosed |
| US-5225554-A | Polyoxa tetracyclic compounds | SRI INTERNATIONAL (US) | 1993-07-06 | — | — | US | disclosed |
| US-5214069-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-25 | — | — | US | disclosed |
| US-5132328-A | Lipoxygenase inhibitors as antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-21 | — | — | US | disclosed |
| US-5098932-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC, ICI PHARMA (FR) | 1992-03-24 | — | — | US | disclosed |
| US-4963683-A | Process for preparing polyoxa tetracyclic compounds | SRI INTERNATIONAL (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |
| EP-0283309-A2 | 1,2-1,4 Addition reaction sequence leading to diphenylacetylenes | McNeilab, Inc. (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4772755-A | 1,2-1,4 addition reaction sequence leading to disubstituted acelylenes | MCNEILAB, INC. (US) | 1988-09-20 | — | — | US | disclosed |