Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380517 | 0.84 | HRH3 (0.50) | CCR1PIK3CAPI4KAPI4KBHRH3 | |
| SCHEMBL2643114 | 0.84 | PIK3CA (0.41) | CCR1PIK3CAPI4KAPI4KBHRH3 | |
| SCHEMBL1373687 | 0.84 | HRH3 (0.42) | MKNK1MKNK2CYSLTR1HRH3HSD17B10 | |
| SCHEMBL3914364 | 0.84 | PIK3CA (0.37) | CCR1PIK3CAPI4KAPI4KBCYSLTR1 | |
| SCHEMBL17247611 | 0.84 | PIK3CA (0.37) | CCR1PIK3CAPI4KAPI4KBCYSLTR1 | |
| SCHEMBL23199281 | 0.84 | CCR1 (0.37) | CCR1PIK3CAPI4KAPI4KBMKNK1 | |
| SCHEMBL16682705 | 0.84 | RECQL (0.36) | CCR1PIK3CAPI4KAPI4KBMKNK1 | |
| SCHEMBL2643146 | 0.84 | PRSS1 (0.34) | CCR1PIK3CAPI4KAPI4KBMKNK1 | |
| SCHEMBL2643113 | 0.84 | PIK3CA (0.37) | CCR1PIK3CAPI4KAPI4KBCYSLTR1 | |
| SCHEMBL1829134 | 0.84 | ABAT (0.34) | CCR1PIK3CAPI4KAPI4KBMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113699689-B | Medical non-woven fabrics of high tension | 江阴市宏勇医疗科技发展有限公司 | 2022-11-25 | — | — | CN | claimed |
| WO-2022143003-A1 | HIGH-BARRIER BOTTLE-GRADE POLYESTER AND PREPARATION METHOD THEREFOR | 江苏恒力化纤股份有限公司 | 2022-07-07 | — | — | WO | claimed |
| CN-112708117-B | High-barrier bottle-grade polyester and preparation method thereof | 江苏恒力化纤股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-112708117-A | High-barrier bottle-grade polyester and preparation method thereof | 江苏恒力化纤股份有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-103524329-B | A kind of method of Carbonylation of Acetylene acrylic acid synthesizing | PUJING CHEMICAL INDUSTRY (SHANGHAI) LIMITED (CN) | 2015-07-29 | — | — | CN | claimed |
| CN-103524329-A | Method for synthesizing acrylic acid through acetylene carbonylation | PUJING CHEMICAL INDUSTRY SHANGHAI LTD | 2014-01-22 | — | — | CN | claimed |
| CN-119613642-A | Modified hydrogen-containing silicon modified oil polyether demulsifier and preparation method thereof | 沈阳中科环境工程科技开发有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-113699689-B | Medical non-woven fabrics of high tension | 江阴市宏勇医疗科技发展有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022143003-A1 | HIGH-BARRIER BOTTLE-GRADE POLYESTER AND PREPARATION METHOD THEREFOR | 江苏恒力化纤股份有限公司 | 2022-07-07 | — | — | WO | disclosed |
| WO-2022143003-A1 | HIGH-BARRIER BOTTLE-GRADE POLYESTER AND PREPARATION METHOD THEREFOR | 江苏恒力化纤股份有限公司 | 2022-07-07 | — | — | WO | disclosed |
| CN-112708117-B | High-barrier bottle-grade polyester and preparation method thereof | 江苏恒力化纤股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-4526787-A | Skin disorders | SRI INTERNATIONAL (US) | 1985-07-02 | — | — | US | disclosed |
| US-4355034-A | Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents | MERCK & CO., INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4217352-A | ANTIARTHRITIC AGENT | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4144342-A | ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4096123-A | COPOLYMER CONTAINING A TERTIARY AMINO GROUP | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1978-06-20 | — | — | US | disclosed |
| US-4061759-A | ANTIINFLAMMATORY, ARTHRITIS | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4053606-A | ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | CCR1 671/4885PIK3CA 1384/4885PI4KA 560/4885 |
| US-11767334-B2 | Heteroaryl inhibitors of PDE4 | PDE4A, PDE4B, PDE4C | CCR1 671/4885PIK3CA 1384/4885PI4KA 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.