Glycopyrronium

Glycopyrronium

SCHEMBL41436

C[N+]1(C)CCC(OC(=O)C(O)(c2ccccc2)C2CCCC2)C1.[Br-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3CHRM4CHRM5

The experimentally established mechanism targets of Glycopyrronium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 15/20 1.00
CHRM2 known ✓ P08172 8/20 1.00
CHRM4 known ✓ P08173 1/20 1.00
CHRM5 known ✓ P08912 1/20 1.00
CHRM1 known ✓ P11229 1/20 1.00
KCNH2 Q12809 2/20 1.00
HRH1 P35367 1/20 1.00
HTR2B P41595 1/20 1.00
SLC22A1 O15245 1/20 0.65
LMNA P02545 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C19 P33261 1/20 0.62
SLC6A4 P31645 1/20 0.62
ALDH1A1 P00352 1/20 0.61
CYP1A2 P05177 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycopyrronium SCHEMBL1900235 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL2012259 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL417981 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL417980 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL132614 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL2335685 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL131054 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Glycopyrronium SCHEMBL4106576 1.00 CHRM3 (1.00) CHRM3CHRM2KCNH2CHRM4CHRM5
Hexopyrronium SCHEMBL5391795 0.99 CHRM3 (0.98) CHRM3CHRM2KCNH2CHRM4CHRM5
Hexopyrronium SCHEMBL915388 0.99 CHRM3 (0.98) CHRM3CHRM2KCNH2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16685 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094727-A Aerosol delivery device, component thereof and method of manufacturing the same 2026-05-26 CN claimed
CN-224242693-U Novel stigmine injection split charging structure of glycopyrronium bromide 广州曼翔医药有限公司 2026-05-15 CN claimed
CN-117064869-B Capsule type inhalation powder spray and preparation method thereof 山东京卫制药有限公司 2026-05-12 CN claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-12616803-B2 Apparatus for dispensing inhalant medicament METOPI PHARMACEUTICALS, INC. (US) 2026-05-05 US claimed
US-12616654-B2 Stainless steel can for pressurised metered dose inhalers CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-05 US claimed
US-20260102381-A1 Muscarinic Agent Combinations Syremis Therapeutics, Ltd. (IL) 2026-04-16 US claimed
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
US-20260076958-A1 LIQUID FORMULATIONS OF INDACATEROL AERORX THERAPEUTICS INC (US) 2026-03-19 US claimed
US-5525347-A Composition and methods for treating performance anxiety MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) 1996-06-11 US claimed
CN-1123180-A \"Weichangning\"-medicine for curing gastrosis LUO YAJUN (CN) 1996-05-29 CN claimed
EP-0711292-A1 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY KOSMIN, Gerald, Emmanuel (GB) 1996-05-15 EP claimed
WO-1995009006-A1 MONOGLYCERIDE/LACTATE ESTER PERMEATION ENHANCER ALZA CORPORATION (US) 1995-04-06 WO claimed
WO-1995003303-A2 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY STATE OF ISRAEL, REPRESENTED BY THE PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1995-02-02 WO claimed
EP-0452101-A2 Spiro bridged and unbridged heterocyclic compounds ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1991-10-16 EP claimed
US-5053412-A Central nervous system disorders ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1991-10-01 US claimed
US-5008111-A Pretreating skin with anticholinergic quaternary ammonium salt to suppress perspiration SCHERING CORPORATION (US) 1991-04-16 US claimed
US-4824676-A ANTICHOLINERGIC AGENT TO SUPPRESS PERSPIRATION SCHERING CORPORATION (US) 1989-04-25 US claimed
EP-0140434-A2 Pharmaceutical composition with systemic anticholineesterasic, agonistic-cholinergic and antimuscarinic activity PRODOTTI FORMENTI S.r.l. (IT) 1985-05-08 EP claimed