Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349960 | 0.97 | — | — | |
| SCHEMBL11756356 | 0.94 | — | — | |
| SCHEMBL11093609 | 0.94 | TSHR (0.53) | — | |
| Zinc Ion SCHEMBL27531323 | 0.94 | — | — | |
| SCHEMBL1006223 | 0.94 | — | — | |
| SCHEMBL11565386 | 0.94 | TSHR (0.53) | — | |
| SCHEMBL4144405 | 0.94 | — | — | |
| Potassium Ion SCHEMBL2470578 | 0.94 | — | — | |
| Lithium Ion SCHEMBL20543352 | 0.94 | — | — | |
| SCHEMBL26929220 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054353-A1 | MANNOSYL-1 PHOSPHATES, PREPARATION METHOD AND THERAPEUTIC USE, IN PARTICULAR AGAINST THE CDG-IA SYNDROME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-02-26 | — | — | US | disclosed |