SCHEMBL414487

SCHEMBL414487

O=C(O)CCCCc1ccc(F)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.66
RXFP1 Q9HBX9 1/20 0.66
FFAR1 O14842 2/20 0.61
HDAC3 O15379 1/20 0.59
MAPK1 P28482 1/20 0.59
ADRA1A P35348 1/20 0.59
HDAC4 P56524 1/20 0.59
SLC6A3 Q01959 1/20 0.59
HDAC1 Q13547 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC2 Q92769 1/20 0.59
HDAC10 Q969S8 1/20 0.59
HDAC11 Q96DB2 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
HDAC9 Q9UKV0 1/20 0.59
HDAC5 Q9UQL6 1/20 0.59
HSD17B10 Q99714 1/20 0.55
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25293960 0.98 MAPT (0.69) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL9567562 0.98 MAPT (0.69) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL2489624 0.98 MAPT (0.69) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL29655693 0.98 MAPT (0.69) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL655425 0.94 SMN1; SMN2 (0.67) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL7065645 0.89 MAPT (0.79) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL8813092 0.89 SMN1; SMN2 (0.60) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL10327442 0.88 MAPT (0.57) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL9671779 0.87 MAPT (0.83) MAPTRXFP1FFAR1HDAC3MAPK1
SCHEMBL3814880 0.87 MAPT (0.83) MAPTRXFP1FFAR1HDAC3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683805-B Preparation method of cross-linked imidazole functionalized polyether sulphone anion exchange membrane containing benzimidazole structure 浙江工业大学 2022-06-21 CN claimed
CN-113683805-A Preparation method of cross-linked imidazole functionalized polyether sulphone anion exchange membrane containing benzimidazole structure 浙江工业大学 2021-11-23 CN claimed
EP-1154021-B1 Polyhydroxyalkanoate synthase and gene encoding the same enzyme CANON KK (JP) 2010-05-26 EP claimed
EP-1149912-B1 Polyhydroxyalkanoate synthase and gene encoding the same CANON KK (JP) 2010-05-26 EP claimed
EP-1172438-B1 Polyhydroxyalkanoate synthase and gene encoding the same enzyme CANON KK (JP) 2010-05-26 EP claimed
EP-1118629-B1 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KK (JP) 2007-04-25 EP claimed
EP-1138770-B1 Polyhydroxyalkanoate synthase and gene encoding the same enzyme CANON KK (JP) 2006-10-18 EP claimed
CN-1260265-C Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2006-06-21 CN claimed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-20030180899-A1 Process for producing polyhydroxyalkanoates by utilizing microorganisms HONMA TSUTOMU (JP) 2003-09-25 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
CN-1322768-A Polyhydroxy alkanoate and process for producing them with microbe CANON KK (JP) 2001-11-21 CN claimed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN claimed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US claimed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed
CN-117105737-A Method for synthesizing alkyl carboxylic acid compound based on olefin hydrocarboxyl 四川大学 2023-11-24 CN disclosed
EP-0862645-A1 STEREOSELECTIVE MICROBIAL REDUCTION PROCESS SCHERING CORPORATION (US) 1998-09-09 EP disclosed
WO-1997012053-A1 STEREOSELECTIVE MICROBIAL REDUCTION PROCESS SCHERING CORPORATION (US) 1997-04-03 WO disclosed