Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.73 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013456 | 0.87 | CYP2C8 (0.68) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL3015559 | 0.87 | CYP2C8 (0.78) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL3003302 | 0.86 | CYP2C8 (0.67) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL3012352 | 0.85 | CYP2C8 (0.68) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL3002082 | 0.85 | CYP2C8 (1.00) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL30992329 | 0.85 | CYP2C8 (1.00) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL3010742 | 0.84 | CYP2C8 (0.74) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL4002128 | 0.83 | CYP2C8 (0.76) | CYP2C8FFAR1ALOX5MAOAMAOB | |
| SCHEMBL3007487 | 0.82 | CYP2C8 (0.64) | CYP2C8FFAR1MAOAMAOBFYN | |
| SCHEMBL3013908 | 0.82 | CYP2C8 (0.86) | CYP2C8FFAR1ALOX5MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | claimed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | claimed |