Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 9/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139604 | 0.91 | RPS6KA2 (0.34) | TBXAS1RPS6KA2RPS6KA3 | |
| SCHEMBL4144600 | 0.86 | RPS6KA2 (0.32) | RPS6KA2RPS6KA3 | |
| SCHEMBL4145558 | 0.85 | SYK (0.40) | RPS6KA2RPS6KA3 | |
| SCHEMBL4143768 | 0.85 | SYK (0.32) | RPS6KA2RPS6KA3 | |
| SCHEMBL3092098 | 0.81 | SRD5A2 (0.36) | RPS6KA2RPS6KA3 | |
| SCHEMBL4144632 | 0.80 | RPS6KA2 (0.34) | RPS6KA2RPS6KA3 | |
| SCHEMBL3083812 | 0.76 | RPS6KA2 (0.43) | RPS6KA2RPS6KA3 | |
| SCHEMBL3081008 | 0.76 | SRD5A2 (0.38) | RPS6KA2RPS6KA3 | |
| SCHEMBL4146046 | 0.70 | RPS6KA3 (0.42) | RPS6KA2RPS6KA3KDM4C | |
| SCHEMBL4144545 | 0.69 | RPS6KA2 (0.36) | RPS6KA2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | TBXAS1 729/4885RPS6KA2 2578/4885RPS6KA3 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.