Ethylene Glycol

Ethylene Glycol

SCHEMBL4147707

C=CC(=O)OC(=O)/C=C\C(=O)O.OCCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.43
HCAR2 Q8TDS4 9/20 0.42
TP53 P04637 4/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
LMNA P02545 1/20 0.36
ALDH1A1 P00352 5/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.34
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725566 0.91 HCAR2 (0.48) TSHRHCAR2TP53EGLN1EGLN3
SCHEMBL1789504 0.91 HCAR2 (0.48) TSHRHCAR2TP53EGLN1EGLN3
SCHEMBL460475 0.91 HCAR2 (0.48) TSHRHCAR2TP53EGLN1EGLN3
Ethylene SCHEMBL6860752 0.89 HCAR2 (0.46) TSHRHCAR2TP53EGLN1EGLN3
Ethylene SCHEMBL28659581 0.89 HCAR2 (0.46) TSHRHCAR2TP53EGLN1EGLN3
SCHEMBL30757889 0.89 HCAR2 (0.46) TSHRHCAR2TP53EGLN1EGLN3
SCHEMBL28820086 0.89 HCAR2 (0.46) TSHRHCAR2TP53EGLN1EGLN3
Maleic Acid SCHEMBL1672343 0.87 TSHR (0.50) TSHRHCAR2TP53EGLN1EGLN3
Ethylene Glycol SCHEMBL27849780 0.84 TSHR (0.56) TSHRTP53LMNAALDH1A1HIF1A
SCHEMBL1502682 0.82 TSHR (0.40) TSHRHCAR2TP53LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130419-A1 FOAM SHEET AND PRODUCTION PROCESS THEREOF OJI PAPER CO., LTD (JP) 2009-05-21 US disclosed
US-20080070998-A1 Foam Production Method OJI PAPER CO., LTD. (JP) 2008-03-20 US disclosed
EP-1795553-A1 PROCESS FOR PRODUCING FOAM Oji Paper Co., Ltd. (JP) 2007-06-13 EP disclosed
US-20060210785-A1 Foamed product in a sheet form and method for production thereof OJI PAPER CO., LTD. (JP) 2006-09-21 US disclosed
EP-1647570-A1 FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF Oji Paper Co., Ltd. (JP) 2006-04-19 EP disclosed