Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 13/20 | 1.00 |
| ▸ | CDC25A | P30304 | 8/20 | 1.00 |
| ▸ | CDC25B | P30305 | 8/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ALPL | P05186 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4143469 | 0.92 | ALPG (1.00) | ALPGCDC25ACDC25BL3MBTL1TDP1 | |
| SCHEMBL4137109 | 0.88 | ALPG (1.00) | ALPGCDC25ACDC25BL3MBTL1ALPL | |
| SCHEMBL4155648 | 0.88 | CDC25A (1.00) | ALPGCDC25ACDC25BL3MBTL1ALPL | |
| SCHEMBL6211001 | 0.86 | MAPT (0.82) | ALPGCDC25ACDC25BLMNASMN1; SMN2 | |
| SCHEMBL6192401 | 0.85 | ALPG (0.74) | ALPGCDC25ACDC25BALPLLMNA | |
| SCHEMBL6211327 | 0.83 | CDC25A (0.83) | ALPGCDC25ACDC25BLMNAMAPT | |
| SCHEMBL6192012 | 0.82 | ALPG (0.69) | ALPGCDC25ACDC25BALPLLMNA | |
| SCHEMBL13856844 | 0.78 | ALPG (0.64) | ALPGCDC25ACDC25BALPLLMNA | |
| SCHEMBL6213562 | 0.78 | ALPG (0.64) | ALPGCDC25ACDC25BALPLLMNA | |
| SCHEMBL6844152 | 0.78 | ALPG (0.75) | ALPGCDC25ACDC25BL3MBTL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078587-A2 | COMPOSITION FOR PREVENTION AND TREATMENT OF CANCER CONTAINING TRIAZOLYL-THIO-ETHANONE DERIVATIVES INHIBITING ACTIVITY OF PROTEIN PHOSPHATASES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS AN ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-06-25 | — | — | WO | claimed |