SCHEMBL4148522

SCHEMBL4148522

CN=C=O.N=C=O.N=C=O

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.75
CASP1 P29466 1/20 0.75
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28690518 1.00 TSHR (0.75) TSHRCASP1ALDH1A1
SCHEMBL28561152 1.00 TSHR (0.75) TSHRCASP1ALDH1A1
SCHEMBL28216787 1.00
Methane SCHEMBL131438 0.96 TSHR (0.69) TSHRCASP1
Methane SCHEMBL825425 0.96 TSHR (0.69) TSHRCASP1
Methane SCHEMBL29199821 0.96 TSHR (0.69) TSHRCASP1
Methane SCHEMBL2903398 0.96 TSHR (0.69) TSHRCASP1
Cyclohexane SCHEMBL29019615 0.89 TSHR (0.60) TSHRCASP1ALDH1A1
Cyclohexane SCHEMBL28402579 0.89 TSHR (0.60) TSHRCASP1ALDH1A1
Cyclohexane SCHEMBL27772263 0.89 TSHR (0.60) TSHRCASP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117242110-A Aqueous polyurethane dispersions 波士胶公司 2023-12-15 CN disclosed
CN-116568720-A Nonionic hydrophilized polyisocyanates having very low monomer contents 科思创德国股份有限公司 2023-08-08 CN disclosed
CN-115397893-A Organic silicon-based thermoplastic material for 3D printing 设置性能股份有限公司 2022-11-25 CN disclosed
CN-109716216-B Photochromic lens and polymerizable composition 三井化学株式会社 2021-05-07 CN disclosed
CN-111333803-A Optical resin composition, optical resin material and application thereof 万华化学集团股份有限公司 2020-06-26 CN disclosed
CN-105793315-A Epoxy resin composition, and film, prepreg and fiber-reinforced plastic using same 三菱丽阳株式会社 2016-07-20 CN disclosed
US-20090076240-A1 COMPOUNDS HAVING ISOCYANATE FUNCTIONAL GROUP SUBSTITUENTS AND COATING COMPOSITIONS COMPRISED THEREOF RHODIA OPERATIONS (FR) 2009-03-19 US disclosed
US-20090054613-A1 FAST DRYING POLYURETHANE COMPOSITION RHODIA, INC. (US) 2009-02-26 US disclosed
EP-1966168-A1 COMPOUND HAVING ISOCYANATE FUNCTIONALITY, PREPARATION THEREOF AND USE THEREOF IN A PROCESS FOR PREPARING A COATING Rhodia Opérations (FR) 2008-09-10 EP disclosed
WO-2007060251-A1 COMPOUND HAVING ISOCYANATE FUNCTIONALITY, PREPARATION THEREOF AND USE THEREOF IN A PROCESS FOR PREPARING A COATING RHODIA OPERATIONS (FR) 2007-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076240-A1 COMPOUNDS HAVING ISOCYANATE FUNCTIONAL GROUP SUBSTITUENTS AND COATING COMPOSITIONS COMPRISED THEREOF HDAC1, HDAC11, HDAC3 TSHR 4440/4885CASP1 1809/4885ALDH1A1 2388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.