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Sugi Predict / Compounds / SCHEMBL4150941

SCHEMBL4150941

SCHEMBL4150941

O=C(NC1CC1)c1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Br)cc1

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 9/20 0.62
▸ CNR1 P21554 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4163002 0.97 CNR2 (0.60) CNR2CNR1
SCHEMBL4434129 0.96 CNR2 (0.59) CNR2
SCHEMBL4149740 0.93 CNR2 (0.58) CNR2CNR1
SCHEMBL4138351 0.88 CNR2 (0.61) CNR2
SCHEMBL4430332 0.88 CNR2 (0.79) CNR2
SCHEMBL4150970 0.88 CNR2 (0.79) CNR2CNR1
SCHEMBL4440018 0.86 CNR2 (0.73) CNR2
SCHEMBL4564001 0.85 CNR2 (0.62) CNR2CNR1
SCHEMBL4155108 0.84 CNR2 (0.72) CNR2
SCHEMBL4150039 0.84 CNR2 (0.57) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009078498-A1 BIARYLPYRAZOLE 4-CARBOXAMIDES AS CANNABINOID CB1 RECEPTOR LIGANDS GREEN CROSS CORPORATION (KR) 2009-06-25 — — WO disclosed