Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140757 | 0.83 | TDP1 (0.45) | TDP1ALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL24452452 | 0.83 | TDP1 (0.67) | TDP1ALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL3297500 | 0.81 | NPC1 (0.46) | TDP1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL19801525 | 0.81 | TDP1 (0.44) | TDP1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL29041312 | 0.80 | MAPT (0.49) | TDP1ALDH1A1TSHRKDM4ELMNA | |
| Sumiki'S Acid SCHEMBL50822 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10HTT | |
| Sumiki'S Acid SCHEMBL29706392 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1TSHRHSD17B10HTT | |
| SCHEMBL6447185 | 0.80 | TDP1 (0.69) | TDP1ALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL28791562 | 0.79 | TDP1 (0.58) | TDP1ALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL21525922 | 0.78 | TDP1 (0.67) | TDP1ALDH1A1TSHRCYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016068712-A1 | CRYSTALLIZATION OF FURANIC COMPOUNDS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2016-05-06 | — | — | WO | claimed |
| EP-4077446-B1 | POLYIMINES AND USES THEREOF | BOSTIK SA (FR) | 2023-08-23 | — | — | EP | disclosed |
| US-11066398-B2 | Small molecule c-Myc inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| CN-110177777-A | For producing the method for containing at least two the aromatic compound of amine functional group | 罗地亚经营管理公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-106456616-A | Small molecule C-Myc inhibitors | 斯克利普斯研究院 | 2017-02-22 | — | — | CN | disclosed |
| EP-3082812-A1 | SMALL MOLECULE C-MYC INHIBITORS | The Scripps Research Institute (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | SORRENTO THERAPEUTICS, INC. | 2016-09-15 | — | — | US | disclosed |
| WO-2016068712-A1 | CRYSTALLIZATION OF FURANIC COMPOUNDS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2016-05-06 | — | — | WO | disclosed |
| EP-3015463-A1 | Crystallization of furanic compounds | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2016-05-04 | — | — | EP | disclosed |
| WO-2015089180-A1 | SMALL MOLECULE C-MYC INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-06-18 | — | — | WO | disclosed |
| EP-2762470-A1 | Conversion of carbohydrates to hydroxymethylfurfural (HMF) and derivatives | Archer-Daniels-Midland Company (US) | 2014-08-06 | — | — | EP | disclosed |
| EP-1697354-B1 | ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20090054397-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND | OHI NORIHITO | 2009-02-26 | — | — | US | disclosed |
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| US-20050208582-A1 | Pyrazole compounds and pharmaceutical compositions comprising the compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| EP-1510516-A1 | PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054397-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND | CNKSR1, NR3C2, CSNK2B | TDP1 4520/4885ALDH1A1 2731/4885TSHR 814/4885 |
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | MYC, MYCBP, MYCBP2 | TDP1 4024/4885ALDH1A1 3976/4885TSHR 4300/4885 |
| US-11066398-B2 | Small molecule c-Myc inhibitors | MYC, MYCBP, MYCBP2 | TDP1 4024/4885ALDH1A1 3976/4885TSHR 4300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.