Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.47 |
| ▸ | DRD1 | P21728 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132415 | 0.89 | CHRM2 (0.49) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL38660198 | 0.89 | CHRM2 (0.57) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL17484101 | 0.88 | KCNH2 (0.46) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| Ethylene SCHEMBL28037648 | 0.85 | CHRM2 (0.46) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL225860 | 0.85 | CYP2D6 (0.52) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL29390583 | 0.85 | CYP2D6 (0.52) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28665181 | 0.83 | KDM4E (0.53) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL16491453 | 0.82 | CHRM2 (0.69) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL28037970 | 0.81 | CHRM2 (0.44) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| Potassium Ion SCHEMBL1369188 | 0.81 | CHRM2 (0.49) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149508-A1 | Process for the preparation of substituted phenyl ether compounds | SANDOZ AG (CH) | 2009-06-11 | — | — | US | disclosed |
| CN-101228128-A | A process for the preparation of substituted phenyl ether compounds and rosiglitazone | SANDOZ AG (CH) | 2008-07-23 | — | — | CN | disclosed |
| EP-1910294-A1 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYL ETHER COMPOUNDS AND ROSIGLITAZONE | Sandoz AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007017095-A1 | A PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYL ETHER COMPOUNDS AND ROSIGLITAZONE | SANDOZ AG (CH) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149508-A1 | Process for the preparation of substituted phenyl ether compounds | PPARG, PPARD, PPARA | CHRM2 3108/4885ADRA2A 1864/4885DRD1 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.