Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782484 | 0.89 | PTPN1 (0.71) | PTPN1PTPN2PTPN11 | |
| SCHEMBL3782486 | 0.89 | PTPN1 (0.71) | PTPN1PTPN2PTPN11 | |
| SCHEMBL13012004 | 0.78 | PTPN1 (0.73) | PTPN1PTPN2PTPN11 | |
| SCHEMBL12425743 | 0.73 | PTPN1 (0.71) | PTPN1PTPN2PTPN11 | |
| SCHEMBL14244758 | 0.73 | PTPN1 (0.71) | PTPN1PTPN2PTPN11 | |
| SCHEMBL1240288 | 0.73 | PTPN1 (0.71) | PTPN1PTPN2PTPN11 | |
| SCHEMBL4975794 | 0.73 | PTPN1 (0.70) | PTPN1PTPN2PTPN11 | |
| SCHEMBL952477 | 0.73 | PTPN1 (0.70) | PTPN1PTPN2PTPN11 | |
| SCHEMBL1239683 | 0.72 | PTPN1 (0.79) | PTPN1PTPN2PTPN11 | |
| SCHEMBL12426122 | 0.72 | PTPN1 (0.79) | PTPN1PTPN2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234993-A1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | AstraZeneca AB (SE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009082347-A1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |