Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.65 |
| ▸ | NOD1 | Q9Y239 | 11/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584158 | 0.93 | GLP1R (0.72) | GLP1RNOD1SLC6A5 | |
| SCHEMBL5954492 | 0.93 | GLP1R (0.72) | GLP1RNOD1SLC6A5 | |
| SCHEMBL1811234 | 0.93 | GLP1R (0.72) | GLP1RNOD1SLC6A5 | |
| SCHEMBL14735663 | 0.93 | GLP1R (0.67) | GLP1RNOD1SLC6A5 | |
| SCHEMBL14735664 | 0.93 | GLP1R (0.67) | GLP1RNOD1SLC6A5 | |
| SCHEMBL25850110 | 0.86 | GLP1R (0.73) | GLP1RNOD1 | |
| SCHEMBL29324628 | 0.86 | GLP1R (0.73) | GLP1RNOD1SLC6A5 | |
| SCHEMBL29324606 | 0.86 | GLP1R (0.73) | GLP1RNOD1SLC6A5 | |
| SCHEMBL13024330 | 0.86 | GLP1R (0.73) | GLP1RNOD1SLC6A5 | |
| SCHEMBL4004880 | 0.85 | GLP1R (0.63) | GLP1RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068910-A2 | USE OF EXENDINS AND EXENDIN AGONISTS AND GLP-1 RECEPTOR AGONISTS FOR ALTERING LIPOPROTEIN PARTICLE SIZE AND SUBCLASS COMPOSITION | Amylin Pharmaceuticals, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019143-A9 | USE OF EXENDINS AND GLP-I RECEPTOR AGONISTS FOR ALTERING LIPOPROTEIN PARTICLE SIZE AND SUBCLASS COMPOSITION | AMYLIN PHARMACEUTICALS INC (US) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008019143-A2 | USE OF EXENDINS AND GLP-I RECEPTOR AGONISTS FOR ALTERING LIPOPROTEIN PARTICLE SIZE AND SUBCLASS COMPOSITION | AMYLIN PHARMACEUTICALS, INC (US) | 2008-02-14 | — | — | WO | disclosed |