⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433038 | 0.85 | — | — | |
| SCHEMBL1498735 | 0.80 | — | — | |
| SCHEMBL5162890 | 0.79 | HMGCR (0.39) | — | |
| SCHEMBL15637781 | 0.78 | — | — | |
| SCHEMBL20141352 | 0.76 | — | — | |
| SCHEMBL664039 | 0.72 | — | — | |
| SCHEMBL27344394 | 0.72 | — | — | |
| SCHEMBL9342 | 0.72 | — | — | |
| SCHEMBL20141641 | 0.69 | — | — | |
| SCHEMBL6989643 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10453 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344986-A | Strain for producing beta-carotene by using cheap nitrogen source, construction method and application thereof | 南京工业大学 | 2024-07-16 | — | — | CN | claimed |
| EP-4392564-A1 | MICROBIAL FERMENTATION FOR THE PRODUCTION OF ISOPRENOID ALCOHOLS AND DERIVATIVES | Lanzatech, Inc. (US) | 2024-07-03 | — | — | EP | claimed |
| CN-118240674-A | Recombinant pichia pastoris for producing retinol, construction method and application thereof | 南京工业大学 | 2024-06-25 | — | — | CN | claimed |
| CN-116144518-B | Saccharomyces cerevisiae strain for producing retinol and application thereof | 江南大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118207176-A | NAD (H) analogue dependent 3-hydroxy-3-methylglutaryl coenzyme A reductase mutant and application thereof | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | claimed |
| CN-118197413-A | Method, system and equipment for screening cholesterol-lowering drugs based on coliform bacteria and central venous hepatocytes | 瓯江实验室 | 2024-06-14 | — | — | CN | claimed |
| WO-2024121558-A1 | ENZYME HAVING PEPULSOL SYNTHASE ACTIVITY | THE UNIVERSITY OF YORK (GB) | 2024-06-13 | — | — | WO | claimed |
| CN-118146970-A | Recombinant pichia pastoris for producing astaxanthin as well as construction method and application thereof | 南京工业大学 | 2024-06-07 | — | — | CN | claimed |
| CN-116790393-B | Method for synthesizing active VD3 by modifying saccharomyces cerevisiae and taking glucose as substrate | 江南大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118086084-A | Lipolytica rhodotorula strain for synthesizing squalene and application thereof | 江南大学 | 2024-05-28 | — | — | CN | claimed |
| US-4956288-A | GENETIC ENGINEERING TO PRODUCE PROTEINS AND POLYPEPTIDES | BIOGEN, INC. (US) | 1990-09-11 | — | — | US | claimed |
| US-4937255-A | Disubstituted pyrroles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | claimed |
| EP-0373507-A1 | Combination of an HMG CoA reductase inhibitor and other type of serum cholesterol reducing agent and method for lowering serum cholesterol using such combination | E.R. SQUIBB & SONS, INC. (US) | 1990-06-20 | — | — | EP | claimed |
| EP-0352575-A2 | Substituted annealed pyrroles | BAYER AG (DE) | 1990-01-31 | — | — | EP | claimed |
| EP-0343783-A2 | Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA | BTG USA INC (US) | 1989-11-29 | — | — | EP | claimed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | claimed |
| EP-0287890-A1 | Substituted pyrroles | BAYER AG (DE) | 1988-10-26 | — | — | EP | claimed |
| EP-0276823-A2 | 14,15-Substituted lanosterols and their use as hypocholesterolemic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-08-03 | — | — | EP | claimed |
| US-4665026-A | Enzymatic synthesis of (S)3-hydroxy-3-methylglutaryl coenzyme A | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2199 ADDISON ST., BERKELEY, CA. 94720 A CA CORP. | 1987-05-12 | — | — | US | claimed |
| EP-0010299-B1 | PHARMACEUTICAL COMPOSITION USEFUL FOR THE TREATMENT OF HYPERCHOLESTEREMIA | MERCK & CO. INC. (US) | 1984-02-15 | — | — | EP | claimed |