SCHEMBL4154727

SCHEMBL4154727

CCO/C(C)=N\O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL513886 1.00
SCHEMBL513885 1.00
SCHEMBL8022541 0.77
SCHEMBL11621776 0.75
SCHEMBL8546157 0.75
SCHEMBL11996350 0.75
SCHEMBL23913817 0.73
SCHEMBL6036832 0.73
SCHEMBL10081779 0.73
SCHEMBL10063335 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075504-A Reacting nitrile with alcohol in presence of hydrogen halide, then treatment with aqueous carbonates and hydroxylamine salts basification, alkylation, acid hydrolysis CIBA-GEIGY CORPORATION (US) 1991-12-24 US claimed
US-20230324398-A1 REAGENT FOR MASS SPECTROMETRY ROCHE DIAGNOSTICS GMBH (DE) 2023-10-12 US disclosed
US-20230324398-A1 REAGENT FOR MASS SPECTROMETRY ROCHE DIAGNOSTICS GMBH (DE) 2023-10-12 US disclosed
CN-116650467-A Immediate release dosage regimen of S1P modulator 诺华股份有限公司 2023-08-29 CN disclosed
WO-2022170075-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2022-08-11 WO disclosed
US-20190047951-A1 AZETIDINE MODULATORS OF THE SPHINGOSINE 1-PHOSPHATE RECEPTOR AUSPEX PHARMACEUTICALS, INC. 2019-02-14 US disclosed
EP-3400211-A1 AZETIDINE MODULATORS OF THE SPHINGOSINE 1-PHOSPHATE RECEPTOR Auspex Pharmaceuticals, Inc. (US) 2018-11-14 EP disclosed
US-9743667-B2 Substituted benzene fungicides E I DU PONT DE NEMOURS AND COMPANY (US) 2017-08-29 US disclosed
US-9743667-B2 Substituted benzene fungicides E I DU PONT DE NEMOURS AND COMPANY (US) 2017-08-29 US disclosed
WO-2017120124-A1 AZETIDINE MODULATORS OF THE SPHINGOSINE 1-PHOSPHATE RECEPTOR AUSPEX PHARMACEUTICALS, INC. (US) 2017-07-13 WO disclosed
US-7220763-B2 Indole-type derivatives as inhibitors of p38 kinase SCIOS, INC. (US) 2007-05-22 US disclosed
US-7220763-B2 Indole-type derivatives as inhibitors of p38 kinase SCIOS, INC. (US) 2007-05-22 US disclosed
US-7183284-B2 Aminium salts of 1,2,3-triazoles as prodrugs of drugs including antiviral agents BRISTOL-MYERS SQUIBB COMPANY (US) 2007-02-27 US disclosed
US-7183284-B2 Aminium salts of 1,2,3-triazoles as prodrugs of drugs including antiviral agents BRISTOL-MYERS SQUIBB COMPANY (US) 2007-02-27 US disclosed
US-5684200-A MULTISTAGE PROCESS OF HYDROXYLAMINES REACTED WITH ALKYLATION AGENT WITH DESULFONATION TO FORM INTERMEDIATES FOR CROP PROTECTION AND DRUGS BASF AKTIENGESELLSCHAFT (DE) 1997-11-04 US disclosed
US-5075504-A Reacting nitrile with alcohol in presence of hydrogen halide, then treatment with aqueous carbonates and hydroxylamine salts basification, alkylation, acid hydrolysis CIBA-GEIGY CORPORATION (US) 1991-12-24 US disclosed
US-4965390-A CHEMICAL INTERMEDIATE FOR HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-10-23 US disclosed
US-4404384-A HYPOTENSIVE, ANTISPASMODIC, CHOLERETIC AGENTS; ANTICONUULSANTS; ANTIPYRETICS; ANTHELMINTICS; FUNGICIDWS HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-13 US disclosed
US-4150043-A 0-(2,3-Epoxypropyl)-hydroximic acid esters HOECHST AKTIENGESELLSCHAFT (DE) 1979-04-17 US disclosed
US-3709920-A METHYLENE-O,O{40 -BIS(ETHYLACETHYDROXIMATE) US AIR FORCE 1973-01-09 US disclosed