Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170612 | 0.96 | CNR2 (0.56) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4163435 | 0.94 | CNR2 (0.58) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4161736 | 0.94 | CNR2 (0.58) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4155178 | 0.94 | CNR2 (0.58) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4165741 | 0.93 | LTB4R2 (0.53) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4162457 | 0.93 | LTB4R2 (0.59) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4156966 | 0.88 | LTB4R2 (0.54) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4330338 | 0.88 | LTB4R2 (0.70) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4165489 | 0.87 | CNR2 (0.56) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4168772 | 0.87 | CNR2 (0.56) | HDAC6HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | HDAC6 1947/4885HDAC1 1912/4885HDAC3 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.