⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599054 | 1.00 | — | — | |
| SCHEMBL22776146 | 0.79 | — | — | |
| SCHEMBL22776147 | 0.79 | — | — | |
| SCHEMBL28922677 | 0.77 | — | — | |
| SCHEMBL30366716 | 0.75 | — | — | |
| SCHEMBL11778457 | 0.73 | — | — | |
| SCHEMBL11778463 | 0.73 | — | — | |
| SCHEMBL22776009 | 0.73 | — | — | |
| SCHEMBL22776097 | 0.73 | — | — | |
| SCHEMBL12002565 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | claimed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | claimed |
| US-11827638-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-28 | — | — | US | disclosed |
| EP-3555096-B1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2022-11-23 | — | — | EP | disclosed |
| CN-114685505-A | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110312719-B | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-20210206768-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2021-07-08 | — | — | US | disclosed |
| US-10981911-B2 | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases | JANSSEN PHARMACEUTICA NV (BE) | 2021-04-20 | — | — | US | disclosed |
| CN-106795146-B | Isoxazole derivatives as inhibitors of mutant isocitrate dehydrogenase 1 | 第一三共株式会社 | 2020-06-26 | — | — | CN | disclosed |
| US-20190322665-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-24 | — | — | US | disclosed |
| EP-3555096-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | Janssen Pharmaceutica NV (BE) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018112382-A1 | IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES | JANSSEN PHARMACEUTICA NV (BE) | 2018-06-21 | — | — | WO | disclosed |
| US-7151075-B2 | 3-(4,5-Dihydroisoxazole-5-yl)benzoylpyrazole | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-19 | — | — | US | disclosed |
| EP-1284969-B1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLCYCLOHEXENONES AND THE USE THEREOF AS HERBICIDES | BASF AG (DE) | 2004-08-18 | — | — | EP | disclosed |
| EP-1240163-B1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLPYRAZOLE | BASF AG (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030100590-A1 | 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-29 | — | — | US | disclosed |
| EP-1284969-A1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLCYCLOHEXENONES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-1240163-A1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLPYRAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001087856-A1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLCYCLOHEXENONES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001046182-A1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLPYRAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-28 | — | — | WO | disclosed |