Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.54 |
| ▸ | CNR1 | P21554 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153149 | 0.95 | CNR2 (0.59) | CNR2CNR1GAAEGFRMAPK14 | |
| SCHEMBL4176963 | 0.86 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL4160813 | 0.86 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL1622013 | 0.84 | CNR2 (0.63) | CNR2MAPK14MAPTLMNAMAPK13 | |
| SCHEMBL1621618 | 0.83 | CNR2 (0.67) | CNR2CNR1GAAEGFRMAPK14 | |
| SCHEMBL4172770 | 0.82 | CNR2 (0.46) | CNR2CNR1GAAEGFRMAPK14 | |
| SCHEMBL4172767 | 0.82 | CNR2 (0.46) | CNR2CNR1GAAEGFRMAPK14 | |
| SCHEMBL1621406 | 0.80 | CNR2 (0.58) | CNR2CNR1GAAEGFRMAPK14 | |
| SCHEMBL10171441 | 0.75 | CNR2 (0.60) | CNR2CNR1GAAEGFRHPGD | |
| SCHEMBL1621510 | 0.74 | CNR2 (0.59) | CNR2MAPK14MAPTLMNAMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |