SCHEMBL4159029

SCHEMBL4159029

Cc1ccccc1-c1nc2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.67
RAB9A P51151 8/20 0.67
MAPT P10636 6/20 0.67
KDM4E B2RXH2 5/20 0.67
ALDH1A1 P00352 5/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
TP53 P04637 4/20 0.67
HSD17B10 Q99714 4/20 0.67
CASP3 P42574 2/20 0.67
SENP8 Q96LD8 2/20 0.67
SENP7 Q9BQF6 2/20 0.67
SENP6 Q9GZR1 2/20 0.67
TSHR P16473 1/20 0.67
HPGD P15428 4/20 0.59
USP2 O75604 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
TOP2A P11388 1/20 0.54
ELANE P08246 1/20 0.54
PTGS2 P35354 1/20 0.54
PKM P14618 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742667 0.93 NPC1 (0.59) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL28774905 0.88 KDM4E (0.55) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL21742591 0.86 NPC1 (0.61) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL171055 0.86 TOP2A (0.62) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL29504749 0.86 TOP2A (0.62) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL12794310 0.85 MAPT (0.59) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL24388803 0.85 NPC1 (0.58) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL12854009 0.84 TOP2A (0.60) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL12776973 0.83 KDM4E (0.58) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL10415954 0.83 KDM4E (0.67) NPC1RAB9AMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119465170-A Rust remover for gas pressure regulating box and preparation method thereof 山东奥德燃气设备制造有限公司 2025-02-18 CN claimed
CN-113201743-B Rust remover suitable for electronic devices and preparation method thereof 浙江工业大学 2022-06-21 CN claimed
CN-113201743-A Rust remover suitable for electronic devices and preparation method thereof 浙江工业大学 2021-08-03 CN claimed
CN-101516860-A Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors NOVARTIS AG (CH) 2009-08-26 CN claimed
CN-119465170-A Rust remover for gas pressure regulating box and preparation method thereof 山东奥德燃气设备制造有限公司 2025-02-18 CN disclosed
US-12018128-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-06-25 US disclosed
EP-4310089-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2024-01-24 EP disclosed
CN-113201743-B Rust remover suitable for electronic devices and preparation method thereof 浙江工业大学 2022-06-21 CN disclosed
US-20220119596-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-04-21 US disclosed
CN-113201743-A Rust remover suitable for electronic devices and preparation method thereof 浙江工业大学 2021-08-03 CN disclosed
CN-108484517-B Benzoxazole compound and synthesis method thereof 信阳师范学院 2021-04-27 CN disclosed
CN-109265409-A A kind of synthetic method of the benzoxazoles that 2- replaces and benzothiazole and its derivative that 2- replaces 重庆医科大学 2019-01-25 CN disclosed
US-5116536-A Preparation of pharmaceutical or cosmetic dispersions BAYER AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
US-4996004-A Preparation of pharmaceutical or cosmetic dispersions BAYER AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed
US-4184977-A WHITENING BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
EP-0000346-B1 QUINOXALINE COMPOUNDS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE AS BRIGHTENERS FOR ORGANIC MATERIALS, AND THE MATERIALS BRIGHTENED THEREWITH BAYER AG (DE) 1980-01-09 EP disclosed
US-4166176-A 2,4-DIOXY-6-/P-VINYLIPHENYLENE/1,3,5-TRIAZINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1979-08-28 US disclosed
EP-0000346-A1 Quinoxaline compounds, process for their manufacture and their use as brighteners for organic materials, and the materials brightened therewith BAYER AG (DE) 1979-01-24 EP disclosed
US-3962056-A MOLDING, COATING EASTMAN KODAK COMPANY (US) 1976-06-08 US disclosed
US-3962055-A MOLDING, COATING EASTMAN KODAK COMPANY (US) 1976-06-08 US disclosed