SCHEMBL415908

SCHEMBL415908

C1=CC2CC1CC2COC(OCC1CC2C=CC1C2)C1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4937724 0.78 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL18719772 0.78 KDM4E (0.39) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL3283085 0.78 KDM4E (0.35) KDM4EALDH1A1LMNA
SCHEMBL416851 0.75 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL7684596 0.75 KDM4E (0.33) KDM4ELMNA
SCHEMBL11068099 0.75 KDM4E (0.37) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL415514 0.74 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL5360041 0.74 KDM4E (0.39) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL15467439 0.74 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL5356106 0.72 KDM4E (0.41) KDM4EALDH1A1TSHRMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 EP disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
US-20230295452-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCLOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2023-09-21 US disclosed
US-20230295452-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCLOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2023-09-21 US disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
WO-2023097092-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2023-06-01 WO disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed
US-4427817-A Open-chain acetals or ketals as non-discoloring antiozonants for rubber BAYER AKTIENGESELLSCHAFT (DE) 1984-01-24 US disclosed
EP-0062809-A1 Use of non-cyclic acetals or ketals as non-discolouring antiozonants BAYER AG (DE) 1982-10-20 EP disclosed