Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL27526284 | 1.00 | GSR (0.61) | GSRLMNATHRBKMT2AMEN1 | |
| Aspartic Acid SCHEMBL31555109 | 0.98 | GSR (0.64) | GSRLMNATHRBKMT2AMEN1 | |
| Octadecylamine SCHEMBL28985934 | 0.90 | GRIK1 (0.54) | GSRKMT2AMEN1ALDH1A1GRIK1 | |
| Lysine SCHEMBL1425215 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 | |
| Lysine SCHEMBL18528930 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 | |
| Lysine SCHEMBL31679370 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 | |
| Lysine SCHEMBL20952564 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 | |
| Lysine SCHEMBL1425217 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 | |
| Lysine SCHEMBL2589784 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 | |
| Lysine SCHEMBL28257457 | 0.90 | GSR (0.80) | GSRNFKB1GRIK1GRIK2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3806593-A1 | RESIST COMPOSITION FOR PATTERN PRINTING USE, AND METHOD FOR MANUFACTURING CIRCUIT PATTERN USING SAME | KANEKA CORPORATION (JP) | 2021-04-14 | — | — | EP | disclosed |
| US-20210103216-A1 | RESIST COMPOSITION FOR PATTERN PRINTING, AND PRODUCTION METHOD OF CIRCUIT PATTERNS USING THE SAME | KANEKA CORPORATION (JP) | 2021-04-08 | — | — | US | disclosed |
| US-20090008050-A1 | METHODS FOR PRODUCING WET-SPUN NON-WOVEN FABRICS | OJI PAPER CO. LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-0949290-B1 | Crosslinked polymer particle and its production process and use | NIPPON CATALYTIC CHEM IND (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-20050266758-A1 | Wet-spun non-woven fabric and method for producing the same | OJI PAPER CO. LTD. (JP) | 2005-12-01 | — | — | US | disclosed |
| US-6410616-B1 | WATER SWELLING | NIPPON SHOKUBAI CO., LTD (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-0949290-A2 | Crosslinked polymer particle and its production process and use | Nippon Shokubai Co., Ltd. (JP) | 1999-10-13 | — | — | EP | disclosed |