Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 7/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159603 | 0.82 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL3792423 | 0.81 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL4155308 | 0.80 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1HPGDPDK1PDK2 | |
| SCHEMBL23029465 | 0.79 | HPGD (0.59) | HSP90AA1ACHEHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL15000795 | 0.78 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1HPGDSMN1; SMN2 | |
| SCHEMBL19409984 | 0.78 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1HPGDPDK1PDK2 | |
| SCHEMBL4147789 | 0.78 | HSP90AB1 (0.58) | HSP90AA1HSP90AB1HPGDPDK1PDK2 | |
| SCHEMBL4163339 | 0.77 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1HPGDPDK1PDK2 | |
| SCHEMBL4147402 | 0.77 | HSP90AB1 (0.51) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL4161521 | 0.77 | PARP10 (0.49) | HSP90AA1HSP90AB1SMN1; SMN2PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | claimed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885HSP90AB1 1/4885ACHE 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.