SCHEMBL4160447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4160452	1.00	DRD3 (0.44)	DRD3DYRK1ANTRK1CNR1CNR2
	SCHEMBL4142437	0.90	MCHR1 (0.44)	DRD3SLC6A12KDRCHEK1CDK1
	SCHEMBL4142435	0.90	MCHR1 (0.44)	DRD3SLC6A12KDRCHEK1CDK1
	SCHEMBL4152746	0.89	DRD3 (0.47)	DRD3DYRK1ANTRK1CNR1CNR2
	SCHEMBL4152742	0.89	DRD3 (0.47)	DRD3DYRK1ANTRK1CNR1CNR2
	SCHEMBL4140646	0.89	KDM4E (0.46)	DRD3DYRK1ACNR1CNR2SLC6A12
	SCHEMBL4140651	0.89	KDM4E (0.46)	DRD3DYRK1ACNR1CNR2SLC6A12
	SCHEMBL4156418	0.89	SMYD3 (0.40)	DRD3CNR1CNR2SLC6A12KDR
	SCHEMBL4156424	0.89	SMYD3 (0.40)	DRD3CNR1CNR2SLC6A12KDR
	SCHEMBL4145331	0.88	DYRK1A (0.42)	DRD3DYRK1ANTRK1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.