SCHEMBL4162168

SCHEMBL4162168

CCOC(OCC)(OCC)C(OCCF)OCCOc1ccc2nc(-c3ccc(N(C)C)cc3)cn2c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 19/20 0.52
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4154941 0.83 APP (0.69) APP
SCHEMBL13453287 0.83 APP (0.69) APP
SCHEMBL4150959 0.82 APP (0.63) APP
SCHEMBL4152910 0.82 APP (0.63) APP
SCHEMBL4142197 0.80 APP (0.51) APP
SCHEMBL12903849 0.70 APP (1.00) APP
SCHEMBL2817233 0.69 APP (0.62) APPHRH3
SCHEMBL12903856 0.69 APP (0.78) APP
SCHEMBL16212419 0.67 TLR9 (0.70) APPHRH3
SCHEMBL2256979 0.66 KDM4E (0.53) APPHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1893245-A4 RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS UNIV PENNSYLVANIA (US) 2009-06-24 EP disclosed
EP-1893245-A2 RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS The Trustees of the University of Pennsylvania (US) 2008-03-05 EP disclosed
US-20070031328-A1 Radiolabeled-pegylation of ligands for use as imaging agents NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-02-08 US disclosed
WO-2007002540-A2 RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS KUNG HANK F (US) 2007-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070031328-A1 Radiolabeled-pegylation of ligands for use as imaging agents EGFR, LANCL1, FLT1 APP 4458/4885HRH3 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.