⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679981 | 0.78 | — | — | |
| SCHEMBL13767376 | 0.75 | — | — | |
| SCHEMBL5471931 | 0.75 | TDP1 (0.44) | — | |
| SCHEMBL8748977 | 0.75 | — | — | |
| SCHEMBL7401748 | 0.75 | — | — | |
| SCHEMBL98764 | 0.75 | — | — | |
| SCHEMBL3644449 | 0.75 | TDP1 (0.44) | — | |
| SCHEMBL80953 | 0.73 | — | — | |
| SCHEMBL19734657 | 0.72 | — | — | |
| SCHEMBL3907719 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111432885-B | Cosmetic composition comprising a silicone material | 美国陶氏有机硅公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-106232100-B | Cross-linking composition and cosmetic composition comprising the same | 美国陶氏有机硅公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-111432885-A | Cosmetic composition comprising silicone material | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | disclosed |
| US-20090137572-A1 | 2-substituted-4-heteroaryl-pyrimidines useful for the treatment of proliferative disorders | CYCLACEL LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| EP-1756098-A2 | 2-SUBSTITUTED-4-HETEROARYL-PYRIMIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Cyclacel Limited (GB) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005116025-A2 | 2-SUBSTITUTED-4-HETEROARYL-PYRIMIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CYCLACEL LIMITED (GB) | 2005-12-08 | — | — | WO | disclosed |