SCHEMBL4164486

SCHEMBL4164486

O=[PH](O)OCCCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26031744 0.90 HDAC3 (0.34)
SCHEMBL26031747 0.90 HDAC3 (0.34)
SCHEMBL3362811 0.83
SCHEMBL902387 0.83
SCHEMBL1070729 0.83
Phosphonic Acid SCHEMBL8385668 0.81
SCHEMBL17061016 0.80 LPAR3 (0.32)
SCHEMBL11744958 0.80 LPAR3 (0.32)
SCHEMBL2467729 0.80 LPAR3 (0.32)
SCHEMBL10946192 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190010174-A1 Crosslinking Monomers With at Least One Sulfur Atom KULZER GMBH (DE) 2019-01-10 US disclosed
EP-3328871-A1 CROSSLINKING MONOMERS WITH AT LEAST ONE ATOM OF SULPHUR Kulzer GmbH (DE) 2018-06-06 EP disclosed
EP-3105269-A1 METHOD FOR PRODUCING DIENE POLYMERS BEARING PHOSPHORUS FUNCTIONAL GROUPS, PRODUCTS RESULTING FROM SAID METHOD AND COMPOSITION CONTAINING SAME Compagnie Générale des Etablissements Michelin (FR) 2016-12-21 EP disclosed
EP-3105260-A1 POLYPHOSPHORUS POLYMER THAT IS THIOL-FUNCTIONALISED AT THE CHAIN ENDS AND PRODUCTION METHOD THEREOF Compagnie Générale des Etablissements Michelin (FR) 2016-12-21 EP disclosed
WO-2015121223-A1 POLYPHOSPHORUS POLYMER THAT IS THIOL-FUNCTIONALISED AT THE CHAIN ENDS AND PRODUCTION METHOD THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
WO-2015121228-A1 PHOSPHORUS DIENE BLOCK COPOLYMER, METHOD FOR THE SYNTHESIS THEREOF AND RUBBER COMPOSITION CONTAINING SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
WO-2015121224-A1 METHOD FOR PRODUCING DIENE POLYMERS BEARING PHOSPHORUS FUNCTIONAL GROUPS, PRODUCTS RESULTING FROM SAID METHOD AND COMPOSITION CONTAINING SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
WO-2015121225-A1 POLYMER BEARING PHOSPHORUS FUNCTIONAL GROUPS AND AT LEAST ONE AZIDE FUNCTIONAL GROUP, METHOD FOR THE SYNTHESIS THEREOF AND USE OF SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS CANNIZZARO CARINA 2009-10-01 US disclosed
US-7432261-B2 Anti-inflammatory phosphonate compounds GILEAD SCIENCES, INC. (US) 2008-10-07 US disclosed
US-20060199788-A1 Anti-inflammatory phosphonate compounds GILEAD SCIENCES, INC. 2006-09-07 US disclosed
EP-1663254-A2 ANTI-INFLAMATORY PHOSPHONATE CONJUGATES GILEAD SCIENCES, INC. (US) 2006-06-07 EP disclosed
WO-2004100960-A2 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-11-25 WO disclosed