SCHEMBL416566

SCHEMBL416566

O=C(OCCCOC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.91
LMNA P02545 3/20 0.70
MAPK1 P28482 2/20 0.61
HIF1A Q16665 1/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A3 Q01959 1/20 0.61
KMT2A Q03164 1/20 0.61
ALDH1A1 P00352 1/20 0.59
F2 P00734 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
TSHR P16473 3/20 0.55
ESR1 P03372 2/20 0.55
ESR2 Q92731 1/20 0.55
SERPINE1 P05121 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C19 P33261 1/20 0.53
NR1H2 P55055 1/20 0.53
RNASEL Q05823 1/20 0.53
NPC1 O15118 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223441 0.95 TDP1 (1.00) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL115000 0.94 TDP1 (0.81) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL22832400 0.94 TDP1 (0.81) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL27782523 0.94 TDP1 (0.81) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL27782522 0.94 TDP1 (0.81) TDP1LMNAMAPK1HIF1ASLC6A2
Ethylene Glycol SCHEMBL7587074 0.94 TDP1 (0.81) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL11896606 0.93 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL2069111 0.93 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL225815 0.93 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL223238 0.93 TDP1 (0.96) TDP1LMNAMAPK1HIF1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596588-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2025-08-06 EP claimed
US-12365785-B2 Glycol ether aryl ester plasticizer EASTMAN CHEMICAL COMPANY (US) 2025-07-22 US claimed
US-12281215-B2 Plasticizer composition, and sealant/adhesive compositions including the same Hanwha Solutions Corporation (KR) 2025-04-22 US claimed
CN-118290625-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-118290624-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-118290623-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
WO-2024088298-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2024-05-02 WO claimed
CN-117924558-A Solid catalyst component for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-117924559-A Solid catalyst component for olefin polymerization and application thereof 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-117924557-A Prepolymerized catalyst for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2024-04-26 CN claimed
EP-2760942-A1 FORMULATIONS HAVING BENZOATE DYE CARRIERS FOR META-ARAMID ARTICLES Dow Global Technologies LLC (US) 2014-08-06 EP claimed
CN-103906812-A Formulations with benzoate dye carriers for meta-aramid articles DOW GLOBAL TECHNOLOGIES INC 2014-07-02 CN claimed
WO-2013048736-A1 FORMULATIONS HAVING BENZOATE DYE CARRIERS FOR META-ARAMID ARTICLES DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-04 WO claimed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
WO-2002102914-A1 HOT MELT ADHESIVE COMPOSITION EASTMAN CHEMICAL COMPANY (US) 2002-12-27 WO claimed
US-20020193474-A1 Hot melt adhesive composition EASTMAN CHEMICAL COMPANY A CORPORATION OF DELAWARE 2002-12-19 US claimed
EP-0603384-B1 HOT MELT ADHESIVE COMPOSITION FULLER H B LICENSING FINANC (US) 2002-10-16 EP claimed
US-4516979-A Polybenzoates as disperse dyeing assistants SANDOZ LTD. (CH) 1985-05-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365785-B2 Glycol ether aryl ester plasticizer DAGLA, DDT, PPARG TDP1 1253/4885LMNA 1384/4885MAPK1 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.