SCHEMBL4166333

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4165439	0.91	CDK2 (0.84)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL4163444	0.90	CDK2 (0.82)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL4172272	0.89	CDK2 (0.81)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL2073867	0.89	CDK2 (1.00)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL2075987	0.89	CDK2 (1.00)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL2074623	0.89	CDK2 (0.81)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL4158736	0.86	CDK2 (0.82)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL2073428	0.85	CDK2 (1.00)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL2076216	0.85	CDK2 (1.00)	CDK2AURKACDK4AURKBCCNE1
	SCHEMBL27664900	0.85	CDK2 (0.85)	CDK2AURKACDK4AURKBCCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.