SCHEMBL4166487

SCHEMBL4166487

OCN1CCCC1(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6129773 0.77
SCHEMBL3873641 0.72
SCHEMBL3876250 0.69
SCHEMBL11497506 0.66 POLB (0.33)
SCHEMBL2058181 0.65
SCHEMBL11304840 0.63 S1PR1 (0.39)
SCHEMBL18546640 0.62
SCHEMBL4051677 0.60
SCHEMBL921200 0.58
SCHEMBL25350273 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11965178-B2 Platelets loaded with anti-cancer agents CELLPHIRE, INC. (US) 2024-04-23 US disclosed
US-20230248771-A1 PLATELETS LOADED WITH ANTI-CANCER AGENTS CELLPHIRE, INC. (US) 2023-08-10 US disclosed
US-20230149468-A1 PLATELET DERIVED EXTRACELLULAR VESICLES CELLPHIRE, INC. (US) 2023-05-18 US disclosed
US-20220202821-A1 SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-06-30 US disclosed
EP-3947351-A2 SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF Board of Regents, The University of Texas System (US) 2022-02-09 EP disclosed
WO-2021232015-A1 PLATELET DERIVED EXTRACELLULAR VESICLES CELLPHIRE, INC. (US) 2021-11-18 WO disclosed
EP-3887404-A1 PLATELETS LOADED WITH ANTI-CANCER AGENTS Cellphire, Inc. (US) 2021-10-06 EP disclosed
EP-3837385-A1 METHODS FOR ASSESSING AND TREATING CANCER The Johns Hopkins University (US) 2021-06-23 EP disclosed
US-20200377956-A1 METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER THE JOHNS HOPKINS UNIVERSITY 2020-12-03 US disclosed
WO-2020205646-A2 SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-10-08 WO disclosed
WO-2019067092-A1 METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2019-04-04 WO disclosed
US-20180339063-A1 BIODEGRADABLE POLYMERIC NANOPARTICLE CONJUGATES AND USE THEREOF NEW YORK UNIVERSITY 2018-11-29 US disclosed
WO-2017083659-A1 BIODEGRADABLE POLYMERIC NANOPARTICLE CONJUGATES AND USE THEREOF NEW YORK UNIVERSITY (US) 2017-05-18 WO disclosed
US-20140255426-A1 WNT PATHWAY INHIBITORS FOR TREATING VIRAL INFECTIONS EMORY UNIVERSITY (US) 2014-09-11 US disclosed
CN-102770419-A Dihydrofuran derivatives as pesticidal compounds SYNGENTA PARTICIPATIONS A G 2012-11-07 CN disclosed
CN-102762544-A Isoxazoline derivatives as insecticides SYNGENTA PARTICIPATIONS AG 2012-10-31 CN disclosed
US-20090233307-A1 METHODS FOR DETECTION OF SINGLE STRAND BREAKS IN DNA THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2009-09-17 US disclosed
US-20090012088-A1 Compounds for the Treatment of Neurodegeneration and Stroke THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2009-01-08 US disclosed
US-20070032496-A1 Compounds for the Treatment of Neurodegeneration and Stroke THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2007-02-08 US disclosed
WO-2007014226-A2 COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATION AND STROKE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2007-02-01 WO disclosed