SCHEMBL4166844

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4170647	0.89	MCL1 (0.49)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL4162321	0.89	MCL1 (0.49)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL4164110	0.89	MCL1 (0.50)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL4170079	0.86	MCL1 (0.56)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL4165286	0.83	MCL1 (0.60)	MARK3NEK4PRKCDCAMK2BCAMK2G
	SCHEMBL4158786	0.83	MCL1 (0.49)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL4166001	0.83	MCL1 (0.53)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL4168089	0.82	MCL1 (0.57)	MCL1HTR6HTR1ADRD2DRD4
	SCHEMBL4165824	0.82	NEK4 (0.60)	MARK3NEK4PRKCDMAP4K2CAMK2B
	SCHEMBL15622097	0.82	MCL1 (0.71)	MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.