Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dicyclomine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 5/20 | 0.97 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.97 |
| ▸ | LMNA | P02545 | 4/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.97 |
| ▸ | TSHR | P16473 | 4/20 | 0.97 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.97 |
| ▸ | DRD1 | P21728 | 2/20 | 0.97 |
| ▸ | DRD3 | P35462 | 2/20 | 0.97 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.97 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.97 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dicyclomine SCHEMBL5501641 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL20536388 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL7023518 | 0.99 | CYP3A4 (0.97) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL3317 | 0.99 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL6285092 | 0.97 | CYP3A4 (0.95) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL10684080 | 0.97 | CYP3A4 (0.97) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL14322178 | 0.97 | CYP3A4 (0.97) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL3051663 | 0.96 | CYP3A4 (0.95) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL16534571 | 0.95 | CYP3A4 (0.90) | CYP3A4MEN1KMT2ATDP1MAPK1 | |
| Dicyclomine SCHEMBL8082728 | 0.95 | CYP3A4 (0.90) | CYP3A4MEN1KMT2ATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4483 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672877-B2 | METHOD AND DEVICE FOR PRODUCING A BLANK FROM A PACKAGING MATERIAL | FOCKE & CO (DE) | 2026-05-13 | — | — | EP | claimed |
| US-20250275924-A1 | Anticholinergic Agents and Muscarinic Agonists for the Treatment of Demodex Related Conditions | ATTILLAPS HOLDINGS INC. | 2025-09-04 | — | — | US | claimed |
| WO-2025133679-A1 | COMPOUNDS AND COMPOSITION FOR DNA PROTECTION | ASSOCIAÇÃO PARA DESENVOLVIMENTO DO CENTRO ACADÉMICO DE INVESTIGAÇÃO E FORMAÇÃO BIOMÉDICA DO ALGARVE, AD-ABC (PT) | 2025-06-26 | — | — | WO | claimed |
| EP-4511123-A1 | ANTICHOLINERGIC AGENTS AND MUSCARINIC AGONISTS FOR THE TREATMENT OF DEMODEX RELATED CONDITIONS | Attillaps Holdings Inc. (US) | 2025-02-26 | — | — | EP | claimed |
| US-20250032503-A1 | USE OF APREPITANT FOR TREATING ALZHEIMER'S DISEASE | HOTH THERAPEUTICS, INC. | 2025-01-30 | — | — | US | claimed |
| CN-119384294-A | Anticholinergic agents and muscarinic agonists for the treatment of Demodex related conditions | 阿提莱普斯控股有限公司 | 2025-01-28 | — | — | CN | claimed |
| US-20240282425-A1 | AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS | LOW GORDON KEITH (US) | 2024-08-22 | — | — | US | claimed |
| EP-3720774-B1 | PACKAGING MACHINE FOR MANUFACTURING CIGARETTE PACKAGING | FOCKE & CO (DE) | 2024-07-03 | — | — | EP | claimed |
| EP-3018652-B1 | SCREEN HAVING CHANGEABLE DISPLAY AREA, MOBILE TERMINAL, AND SCREEN DISPLAY METHOD | HUIZHOU TCL MOBILE COMMUNICATION CO LTD (CN) | 2024-05-29 | — | — | EP | claimed |
| EP-4297868-A1 | USE OF APREPITANT FOR TREATING ALZHEIMER'S DISEASE | Hoth Therapeutics, Inc. (US) | 2024-01-03 | — | — | EP | claimed |
| CN-1195357-A | Polymeric material, method for the production and use thereof | PREFORM GMBH (DE) | 1998-10-07 | — | — | CN | claimed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| EP-0814772-A1 | PECTIN PHARMACEUTICAL COMPOSITIONS | The Boots Company PLC (GB) | 1998-01-07 | — | — | EP | claimed |
| EP-0814773-A1 | PECTIN LIQUID PHARMACEUTICAL COMPOSITIONS | The Boots Company PLC (GB) | 1998-01-07 | — | — | EP | claimed |
| CN-1139431-A | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | PHARMACIA & UPJOHN CO LLC (US) | 1997-01-01 | — | — | CN | claimed |
| CN-1136562-A | Estrogen excitant/antagonist | PFIZER BIG PHARMACEUTICAL FACT (US) | 1996-11-27 | — | — | CN | claimed |
| CN-1133040-A | Benzothiophenes and related compounds as estrogen agonists | PFIZER (US) | 1996-10-09 | — | — | CN | claimed |
| WO-1996029054-A1 | PECTIN PHARMACEUTICAL COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 1996-09-26 | — | — | WO | claimed |
| WO-1996029055-A1 | PECTIN LIQUID PHARMACEUTICAL COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 1996-09-26 | — | — | WO | claimed |
| EP-0661050-A1 | ANALGESIC | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-07-05 | — | — | EP | claimed |