SCHEMBL4167442

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2074623	0.91	CDK2 (0.81)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL4167448	0.90	CDK2 (0.83)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL4172272	0.89	CDK2 (0.81)	CDK2CDK9CDK4AURKAAURKB
	Cyc-116 SCHEMBL2074998	0.89	CDK2 (1.00)	CDK2CDK9CDK4AURKAAURKB
	Cyc-116 SCHEMBL29366353	0.89	CDK2 (1.00)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL29815860	0.87	CDK4 (0.74)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL2076213	0.87	CDK2 (1.00)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL4154271	0.84	CDK2 (1.00)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL4159787	0.84	WEE1 (1.00)	CDK2CDK9CDK4AURKAAURKB
	SCHEMBL27664889	0.84	CDK2 (0.76)	CDK2CDK9CDK4AURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.