SCHEMBL416766

SCHEMBL416766

CCCCC[SiH](CCCCC)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
THRB P10828 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.44
LMNA P02545 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC22A1 O15245 3/20 0.39
SLC22A2 O15244 1/20 0.39
DNM1 Q05193 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033088 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL17090793 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL17090787 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL17090843 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL10416460 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL17090779 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL10416490 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL17090806 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL367967 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA
SCHEMBL475823 0.96 TSHR (0.57) TSHRTHRBSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1054 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003916-B Ultra-soft polypropylene composition and preparation method and application thereof 中国石油化工股份有限公司 2024-08-06 CN claimed
CN-116003916-A Ultra-soft polypropylene composition and preparation method and application thereof 中国石油化工股份有限公司 2023-04-25 CN claimed
CN-112351987-A Non-coordinating anionic activators containing cations with large alkyl groups 埃克森美孚化学专利公司 2021-02-09 CN claimed
US-10150822-B2 Catalyst component for olefin polymerization, preparation method therefor and catalyst thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2018-12-11 US claimed
US-20140163185-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-06-12 US claimed
EP-1785413-B1 ARYLSULFONIC ACID COMPOUND AND USE THEREOF AS ELECTRON-ACCEPTOR MATERIAL NISSAN CHEMICAL IND LTD (JP) 2014-01-22 EP claimed
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-7550760-B2 Polyacenes and electronic devices generated therefrom XEROX CORPORATION (US) 2009-06-23 US claimed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
WO-2005118564-A2 METHODS FOR THE SYNTHESIS OF MILNACIPRAN AND CONGENERS THEREOF COLLEGIUM PHARMACEUTICAL, INC. (US) 2005-12-15 WO claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
EP-1208167-B1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES HEMPELS SKIBSFARVE FAB J C (DK) 2003-07-30 EP claimed
US-5663271-A Polysilanes and method for producing the same RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1997-09-02 US claimed
US-5508397-A Activated macrolactams ABBOTT LABORATORIES (US) 1996-04-16 US claimed
EP-0073559-B1 PROCESS FOR PREPARING DESACETOXYCEPHALOSPORANIC ACID ELI LILLY AND COMPANY (US) 1986-04-02 EP claimed
EP-0073559-A2 Process for preparing desacetoxycephalosporanic acid ELI LILLY AND COMPANY (US) 1983-03-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 TSHR 3690/4885THRB 4122/4885SMN1; SMN2 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.