Aniline

Aniline

SCHEMBL4167989

CCS.Nc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.65
MAOB P27338 7/20 0.46
MAOA P21397 7/20 0.46
MAPT P10636 5/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP2D6 P10635 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
HSD17B10 Q99714 1/20 0.46
IDO1 P14902 1/20 0.41
TP53 P04637 1/20 0.41
HTT P42858 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL4159756 0.89 TSHR (0.58) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL1767900 0.88 TSHR (0.73) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL10747054 0.85 TSHR (0.69) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL17710404 0.85 TSHR (0.69) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL11815890 0.85 TSHR (0.69) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL27858423 0.85 TSHR (0.69) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL4922167 0.85 TSHR (0.69) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL4164956 0.83 TSHR (0.50) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL27542252 0.82 TSHR (0.65) TSHRMAOBMAOAMAPTCYP3A4
Aniline SCHEMBL2541181 0.82 TSHR (0.65) TSHRMAOBMAOAMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090030099-A1 FOAM COMPOSITION AND FOAM THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-01-29 US disclosed
EP-1724318-A1 METHOD FOR ADHESIVE-BONDING VULCANIZED RUBBER COMPOSITIONS BY THE USE OF THERMOPLASTIC ELASTOMER COMPOSITIONS THE YOKOHAMA RUBBER CO., LTD. (JP) 2006-11-22 EP disclosed
US-20060213605-A1 Method for adhesive-bonding vulcanized rubber compositions by the use of thermoplastic elastomer compositions YOKOHAMA RUBBER CO., LTD., THE (JP) 2006-09-28 US disclosed
US-20060199917-A1 thermoplastic elastomer exhibiting high recyclability and oil resistance as well as excellent mechanical strength, and in particular, excellent resistance to compression set is provided. The thermoplastic resin with epoxy, hydroxy or nitrogen groups in backbone YOKOHAMA RUBBER CO., LTD., THE (JP) 2006-09-07 US disclosed
EP-1695987-A1 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2006-08-30 EP disclosed
US-20060189755-A1 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. 2006-08-24 US disclosed