Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456091 | 1.00 | KDM4E (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL1456096 | 1.00 | — | — | |
| SCHEMBL7900334 | 1.00 | KDM4E (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL3119209 | 1.00 | — | — | |
| SCHEMBL14720962 | 0.96 | — | — | |
| SCHEMBL6882890 | 0.85 | — | — | |
| SCHEMBL6889421 | 0.82 | — | — | |
| SCHEMBL6472581 | 0.82 | — | — | |
| SCHEMBL3304905 | 0.80 | TRIM24 (0.43) | ALDH1A1 | |
| SCHEMBL3309008 | 0.80 | TRIM24 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595424-B1 | Composition and procedure for the preparation of organic glasses | GREAT LAKES CHEMICAL ITALIA (IT) | 1998-05-13 | — | — | EP | claimed |
| US-5599876-A | POLYMERIZABLE LIQUID CONSISTS OF POLYMERIZABLE POLY(ALLYL CARBONATE) OF ALIPHATIC OR CYCLO-ALIPHATIC POLYOL, AN ORGANIC PEROXIDE GENERATOR OF FREE-RADICALS, AN ORGANIC DYE OR PHOTOCHROMIC COMPOUND | ENICHEM SYNTHESIS S.P.A. (IT) | 1997-02-04 | — | — | US | claimed |
| EP-0595424-A2 | Composition and procedure for the preparation of organic glasses | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1994-05-04 | — | — | EP | claimed |
| CN-118871529-A | Thermoplastic resin composition | 三井化学株式会社 | 2024-10-29 | — | — | CN | disclosed |
| WO-2021103798-A1 | METHOD FOR PREPARING LACTONE COMPOUND | 浙江大学 | 2021-06-03 | — | — | WO | disclosed |
| CN-110818671-B | Method for preparing lactone compounds | 浙江大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-110818671-A | Method for preparing lactone compounds | 浙江大学 | 2020-02-21 | — | — | CN | disclosed |
| EP-2636665-B1 | METHOD FOR PRODUCING ESTER | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-06-22 | — | — | EP | disclosed |
| US-8865353-B2 | Nonaqueous electrolyte and lithium cell using the same | UBE INDUSTRIES, LTD. (JP) | 2014-10-21 | — | — | US | disclosed |
| US-8853426-B2 | Method for manufacturing ester | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8853426-B2 | Method for manufacturing ester | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-6906205-B2 | Spiro and dispiro 1,2,4-trioxolane antimalarials | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2005-06-14 | — | — | US | disclosed |
| US-6825230-B2 | PEROXY COMPOUNDS SUCH AS ADAMANTANE-2-SPIRO-3'-8'-((1'S)-10'-CAMPHORSULFONYL)-1',2',4'-TRIOXA-8' -AZASPIRO(4.5) DECANE, USED FOR PROPHYLAXIS OF MALARIA OR SCHISTOSOMIASIS INFECTIONS | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2004-11-30 | — | — | US | disclosed |
| US-20040186168-A1 | Such as spiroadamantane on one side and 4-substituted spiro-cyclohexyl on other side; structurally simple, nontoxic, easy synthesis, potent parasiticides | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2004-09-23 | — | — | US | disclosed |
| EP-1414813-A1 | 1,2,4-TRIOXOLANE ANTIMALARIALS | Medicines for Malaria Venture (CH) | 2004-05-06 | — | — | EP | disclosed |
| US-20040039008-A1 | Spiro and dispiro 1,2,4-trioxolane antimalarials | MEDICINES FOR MALARIA VENTURES MMV (CH) | 2004-02-26 | — | — | US | disclosed |
| WO-2003000676-A1 | 1,2,4-TRIOXOLANE ANTIMALARIALS | MEDICINES FOR MALARIA VENTURE (CH) | 2003-01-03 | — | — | WO | disclosed |
| EP-0595424-B1 | Composition and procedure for the preparation of organic glasses | GREAT LAKES CHEMICAL ITALIA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5599876-A | POLYMERIZABLE LIQUID CONSISTS OF POLYMERIZABLE POLY(ALLYL CARBONATE) OF ALIPHATIC OR CYCLO-ALIPHATIC POLYOL, AN ORGANIC PEROXIDE GENERATOR OF FREE-RADICALS, AN ORGANIC DYE OR PHOTOCHROMIC COMPOUND | ENICHEM SYNTHESIS S.P.A. (IT) | 1997-02-04 | — | — | US | disclosed |
| EP-0595424-A2 | Composition and procedure for the preparation of organic glasses | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1994-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039008-A1 | Spiro and dispiro 1,2,4-trioxolane antimalarials | DHODH, THPO, SQLE | KDM4E 4113/4885ALDH1A1 212/4885MAPT 4003/4885 |
| US-20040186168-A1 | Such as spiroadamantane on one side and 4-substituted spiro-cyclohexyl on other side; structurally simple, nontoxic, easy synthesis, potent parasiticides | DHODH, SQLE, SULT1E1 | KDM4E 3092/4885ALDH1A1 135/4885MAPT 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.