⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140170 | 0.76 | — | — | |
| SCHEMBL707353 | 0.76 | — | — | |
| SCHEMBL2322736 | 0.73 | — | — | |
| SCHEMBL8544011 | 0.73 | — | — | |
| SCHEMBL13906355 | 0.73 | — | — | |
| SCHEMBL17185614 | 0.73 | — | — | |
| SCHEMBL11704753 | 0.73 | — | — | |
| SCHEMBL4058838 | 0.70 | SLC2A1 (0.36) | — | |
| SCHEMBL4306738 | 0.68 | SLC2A1 (0.35) | — | |
| SCHEMBL4239590 | 0.68 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012088-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-08 | — | — | US | disclosed |
| US-20070032496-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2007-02-08 | — | — | US | disclosed |
| WO-2007014226-A2 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATION AND STROKE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-02-01 | — | — | WO | disclosed |