Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176163 | 0.93 | EGFR (1.00) | EGFR | |
| SCHEMBL2730365 | 0.93 | EGFR (1.00) | EGFR | |
| SCHEMBL4172115 | 0.92 | EGFR (1.00) | EGFR | |
| SCHEMBL2731806 | 0.91 | EGFR (1.00) | EGFR | |
| SCHEMBL22745045 | 0.91 | EGFR (0.88) | EGFR | |
| SCHEMBL4176486 | 0.90 | EGFR (1.00) | EGFR | |
| SCHEMBL2732831 | 0.90 | EGFR (0.95) | EGFR | |
| SCHEMBL9946946 | 0.89 | EGFR (1.00) | EGFR | |
| SCHEMBL4179425 | 0.89 | EGFR (0.95) | EGFR | |
| SCHEMBL2723295 | 0.89 | EGFR (1.00) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061299-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |