Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794920 | 1.00 | GAA (0.40) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL3923997 | 0.90 | HMGCR (0.40) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL2683898 | 0.85 | GAA (0.38) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL9674773 | 0.85 | HMGCR (0.40) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL937841 | 0.83 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5030597 | 0.83 | GAA (0.44) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL581163 | 0.81 | HMGCR (0.45) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL870709 | 0.81 | HMGCR (0.45) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL5030601 | 0.81 | GAA (0.43) | GAAKMT2AHMGCRATMNPSR1 | |
| SCHEMBL11770360 | 0.80 | ELANE (0.48) | GAAKMT2APKMHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123507-A1 | Metal Oxide Nanoparticles Coated With Specific N-Acylaminomethylene Phosphonates | CIBA SPECIALTY CHEMICALS CORP. | 2009-05-14 | — | — | US | disclosed |
| US-20060189491-A1 | Lubricating oil composition | SHELL OIL COMPANY | 2006-08-24 | — | — | US | disclosed |
| EP-1683852-A1 | Lubricating oil composition | Shell Internationale Research Maatschappij B.V. (NL) | 2006-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123507-A1 | Metal Oxide Nanoparticles Coated With Specific N-Acylaminomethylene Phosphonates | PHOSPHO1, ACP1, PNN | GAA 1074/4885KMT2A 591/4885HMGCR 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.