SCHEMBL4174064

SCHEMBL4174064

Cc1cc(C(=O)NCC2CCNCC2)nn1Cc1cc(C#N)cc2cc(C(C)C)oc12

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 19/20 0.64
PTGER3 P43115 1/20 0.50
USP30 Q70CQ3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4164351 0.99 PTGER1 (0.64) PTGER1PTGER3USP30
SCHEMBL14397252 0.90 PTGER1 (0.54) PTGER1PTGER3USP30
SCHEMBL13873948 0.90 PTGER1 (0.54) PTGER1PTGER3USP30
SCHEMBL4164358 0.89 PTGER1 (0.81) PTGER1PTGER3
Hydrochloric Acid SCHEMBL4157428 0.88 PTGER1 (0.80) PTGER1PTGER3
SCHEMBL13424496 0.86 PTGER1 (0.81) PTGER1USP30
SCHEMBL4162516 0.86 PTGER1 (0.50) PTGER1PTGER3USP30
Hydrochloric Acid SCHEMBL3223891 0.85 PTGER1 (0.80) PTGER1USP30
SCHEMBL4160611 0.82 PTGER1 (0.73) PTGER1PTGER3
SCHEMBL4167748 0.81 PTGER1 (0.60) PTGER1PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090099169-A1 Benzofuran Compounds As EP1 Receptor Antagonists GLAXO GROUP LIMITED (GB) 2009-04-16 US claimed
US-20090099169-A1 Benzofuran Compounds As EP1 Receptor Antagonists GLAXO GROUP LIMITED (GB) 2009-04-16 US disclosed
US-20090099169-A1 Benzofuran Compounds As EP1 Receptor Antagonists GLAXO GROUP LIMITED (GB) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099169-A1 Benzofuran Compounds As EP1 Receptor Antagonists PTGER1, PTGER2, PTGER3 PTGER1 1/4885PTGER3 3/4885USP30 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.