Sugi Predict

Sugi Predict / Compounds / SCHEMBL4174679

SCHEMBL4174679

SCHEMBL4174679

Cc1c(C)n(CCCCCCSc2nnnn2C)c2ccc3[nH]c(=O)cc(C(F)(F)F)c3c12

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 12/20 0.37
▸ GAA P10253 1/20 0.34
▸ S1PR2 O95136 1/20 0.32
▸ NR3C1 P04150 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ PGR P06401 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4169689 0.82 AR (0.43) ARNR3C1PGR
SCHEMBL4176201 0.82 AR (0.43) ARNR3C1PGR
SCHEMBL4172488 0.82 AR (0.43) ARNR3C1PGR
SCHEMBL4172416 0.81 AR (0.47) ARNR3C1PGR
SCHEMBL4170320 0.81 AR (0.47) ARNR3C1PGR
SCHEMBL4180225 0.81 AR (0.47) ARNR3C1PGR
SCHEMBL4189561 0.81 AR (0.45) ARALDH1A1LMNATP53NPSR1
SCHEMBL13697666 0.81 AR (0.40) ARNR3C1PGR
SCHEMBL4172779 0.80 AR (0.44) ARNR3C1PGR
SCHEMBL4172067 0.80 AR (0.44) ARNR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US claimed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods AR, NR5A1, ESRRA AR 1/4885GAA 4594/4885S1PR2 1374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.