Sugi Predict

Sugi Predict / Compounds / SCHEMBL4175518

SCHEMBL4175518

SCHEMBL4175518

Cc1c(C)n(CCCCCCCCCOCCN2CCCCC2)c2ccc3[nH]c(=O)cc(C(F)(F)F)c3c12

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 13/20 0.37
▸ NUAK1 O60285 1/20 0.34
▸ NR3C1 P04150 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ HRH3 Q9Y5N1 1/20 0.34
▸ HTR2A P28223 1/20 0.34
▸ HTR2C P28335 1/20 0.34
▸ HTR2B P41595 1/20 0.34
▸ PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4183090 0.94 AR (0.41) ARNR3C1LMNAPGR
SCHEMBL4178893 0.94 AR (0.41) ARNR3C1LMNAPGR
SCHEMBL4175644 0.93 AR (0.42) ARNR3C1PGR
SCHEMBL4178818 0.85 AR (0.46) ARNUAK1HRH3
SCHEMBL4172074 0.84 AR (0.52) ARNR3C1PGR
SCHEMBL4173006 0.84 AR (0.52) ARNR3C1PGR
SCHEMBL4183790 0.83 AR (0.39) ARNR3C1PGR
SCHEMBL4182448 0.83 AR (0.53) ARNR3C1PGR
SCHEMBL4186335 0.83 AR (0.48) ARNR3C1HTR2AHTR2CHTR2B
SCHEMBL4169288 0.82 AR (0.39) ARNR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US claimed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods AR, NR5A1, ESRRA AR 1/4885NUAK1 2002/4885NR3C1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.