Sugi Predict

Sugi Predict / Compounds / SCHEMBL4175855

SCHEMBL4175855

SCHEMBL4175855

CCc1c(C)c2c3c(C(F)(F)F)cc(=O)[nH]c3ccc2n1CCCCCCCCCS(=O)(=O)CCCCO

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 14/20 0.50
▸ KDM4E B2RXH2 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ ESR1 P03372 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ ESR2 Q92731 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ NR3C1 P04150 1/20 0.34
▸ PGR P06401 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4179904 0.94 AR (0.56) ARNR3C1PGR
SCHEMBL4189556 0.94 AR (0.56) ARNR3C1PGR
SCHEMBL9885150 0.90 AR (0.58) ARNR3C1PGR
SCHEMBL4174129 0.89 AR (0.51) ARNR3C1PGR
SCHEMBL13697672 0.89 AR (0.51) ARNR3C1PGR
SCHEMBL4178975 0.89 AR (0.51) ARNR3C1PGR
SCHEMBL4176182 0.89 AR (0.51) ARNR3C1PGR
SCHEMBL4170323 0.89 AR (0.51) ARNR3C1PGR
SCHEMBL4180557 0.87 AR (0.49) ARNR3C1PGR
SCHEMBL4182475 0.87 AR (0.49) ARNR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US claimed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED 2009-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227571-A1 Androgen Receptor Modulator Compounds and Methods AR, NR5A1, ESRRA AR 1/4885KDM4E 1594/4885MEN1 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.