Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160759 | 0.88 | S1PR1 (0.81) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL176981 | 0.88 | S1PR1 (1.00) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8866863 | 0.84 | S1PR1 (0.63) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23720579 | 0.84 | S1PR1 (0.63) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8866867 | 0.84 | S1PR1 (0.63) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18862116 | 0.83 | S1PR1 (0.65) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25401865 | 0.82 | S1PR1 (0.76) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10599703 | 0.82 | MAPT (0.67) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4894039 | 0.82 | EPHX1 (0.68) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6571730 | 0.80 | S1PR1 (0.65) | S1PR1ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED | 2009-09-10 | — | — | US | claimed |
| WO-2007005887-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-11 | — | — | WO | claimed |
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | AR, NR5A1, ESRRA | S1PR1 1301/4885ALDH1A1 1408/4885CYP1A2 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.