Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 10/20 | 0.53 |
| ▸ | FLT3 | P36888 | 8/20 | 0.53 |
| ▸ | FLT4 | P35916 | 7/20 | 0.53 |
| ▸ | CSF1R | P07333 | 7/20 | 0.53 |
| ▸ | KDR | P35968 | 12/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170871 | 0.95 | PDGFRB (0.54) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL1098218 | 0.81 | PDGFRB (0.61) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4527222 | 0.79 | PDGFRB (0.69) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4173909 | 0.78 | PDGFRB (0.51) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4520365 | 0.77 | PDGFRB (0.66) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4176628 | 0.76 | PDGFRB (0.81) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4532879 | 0.76 | PDGFRB (0.72) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4513077 | 0.76 | PDGFRB (0.64) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4175038 | 0.76 | FLT4 (0.82) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4178009 | 0.75 | KDR (0.58) | PDGFRBFLT3FLT4CSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233950-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233950-A1 | QUINAZOLINE DERIVATIVES | NQO2, CCNI, F12 | PDGFRB 2332/4885FLT3 77/4885FLT4 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.